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So I left her office with no prescription for pills and instead I started the depo birth control shot, which does not contain estrogen. They can also ease period pains and help with acne, but they may also have some undesirable side effects Read about the different types of birth control pills, drug interactions, the brands of oral contraceptives, and their side effects. It affects a certain natural substance that causes narrowing of blood vessels in the brain. The birth control pill is surrounded by misinformation. 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