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This selection from the eMedTV archives provides a detailed overview of the drug, including information on its uses, dosing guidelines, and possible side effects Some medications used to treat bipolar disorder can increase your appetite All of these medications are known to increase the risk of weight gain except lamotrigine How is bipolar-II disorder treated? 3(4); 2007 Aug Lamotrigine has been suggested as effective in the treatment of comorbid bipolar and borderline personality disorder (Preston et al 2004), comorbid bipolar disorder and alcohol dependence (Rubio et al 2006), and comorbid bipolar disorder and cocaine dependence (Brown et al 2003; Brown E et al 2006) Some people who abruptly stop taking the drug Lamictal for bipolar disorder complain of serious withdrawal symptoms. Average dose was 160 mg/day and was titrated very slowly because of the increased risk of rash in children treated with lamotrigine. 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